lidocaine is a local anesthetic, also known as Xylocaine, in recent years it has been replaced procaine, widely used in local infiltration anesthesia in cosmetic plastic surgery, lidocaine can block the nerve excitability and conduction by inhibiting the sodium channels of nerve cell membrane. The fat soluble and protein binding rate of it is higher than procaine, its cell penetrating ability is strong, fast onset, long duration of action, the interaction strength is 4 times of procaine.
- Additional information
lidocaine CAS 137-58-6 Product Information
|Synonyms:||2-Diethylamino-N-(2,6-dimethylphenyl)acetamide;Lignocaine;2-Diethylamino-N-(2,6-dimethylphenyl)acetamide,Lignocaine,Xylocaine;Maricaine;MFCD08443609;Gravocain;2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide;Lidoderm;N1-(2,6-dimethylphenyl)-2-(diethylamino)acetamide;2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;XYLOCAINE;N-(2,6-Dimethylphenyl)-N,N-diethylglycinamide;2-Diethylamino-2′,6′-acetoxylidide;N-(2,6-Diméthylphényl)-N,N-diéthylglycinamide;Anestacon;L-Caine;Leostesin;Esracaine;Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-;Lidothesin;2-Diethylamino-N-(2,6-dimethylphenyl)acetamide Lignocaine Xylocaine;N-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide;lignocainum hydrochloricum;w-Diethylamino-2,6-dimethylacetanilide;EINECS 205-302-8|
|Boiling Point:||bp4 180-182°; bp2 159-160°|
|Density:||0.9944 (rough estimate)|
|Appearance:||White to slightly yellow powder|
|Applications:||lidocaine is an Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anaesthetic. Neuroprotective & Neuro Research Products.|
|Solubility:||ethanol: 4 mg/mL|
|Storage:||Store at RT|
What is lidocaine?
lidocaine also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. lidocaine is also used to treat ventricular tachycardia. When used for local anaesthesia or in nerve blocks, it typically begins working within several minutes and lasts for half an hour to three hours. lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area. lidocaine is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.
What is lidocaine used for?
lidocaine belongs to the family of medicines called local anesthetics. This medicine prevents pain by blocking the signals at the nerve endings in the skin. This medicine does not cause unconsciousness as general anesthetics do when used for surgery. This medicine is available only with your doctor’s prescription.
How long does lidocaine last?
That really depends on several factors. However, lidocaine is reported to begin numbing a particular area in 90 seconds or so, and numbness can last for about 60 to 90 minutes or longer. Then again, that depends on any of the following conditions.
The dose. The higher the dose, the longer the numbing effect will last. The amount will in turn depend on the type of procedure to be done, the number of nerves involved, and size of the area to be treated. A root canal would require a higher dose than a simple filling procedure.
lidocaine side effects
- Bluish-colored lips, fingernails, or palms blurred or double vision.
- chest pain or discomfort.
- cold, clammy, pale skin.
- continuing ringing or buzzing or other unexplained noise in the ears.
- difficulty breathing.
- difficulty swallowing.
- dizziness or lightheadedness.
White to slightly yellow