Benzocaine (ethyl p-aminobenzoate) is used topically by itself or in combination with menthol or phenol in nonprescription dosage forms such as gels, creams, ointments, lotions, aerosols, and lozenges to relieve pain or irritation caused by such conditions as sunburn, insect bites, toothache, teething, cold sores or canker sores in or around the mouth, and fever blisters. Benzocaine is a lipophilic local anesthetic agent with a short duration of action.
- Additional information
Benzocaine CAS 94-09-7 Product Information
|Synonyms:||4-Aminobenzoic Acid Ethyl Ester;AKOS BBS-00003658;BENZOCAINUM;ETHYL 4-AMINOBENZOATE;ETHYLAMINOBENZOATE-4;H-4-ABZ-OET;LABOTEST-BB LTBB000527;ORTHESIN;P-AMINOBENZOIC ACID ETHYL ESTER;4-(Ethoxycarbonyl)ani|ine;4-amino-benzoicaciethylester;4-Carbethoxyani|ine|
|Boiling Point:||172 °C (12.7517 mmHg)|
|Melting point:||88-90 °C|
|Appearance:||White Crystalline Powder|
|Applications:||Benzocaine, together with all other local anaesthesia (LAs), acted on the common receptor of the voltage-gated Na+ channel, and its IC50 value was 0.8mm at +30 mV.|
|Solubility:||Soluble in ethanol, ch|oroform, ethylether and dilute acids. Sparingly soluble in water|
|Storage:||stored in tight containers and protected from light and not prolonged exposure to temperatures greater than 30 °C|
what is benzocaine
Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is combined with antipyrine to form A/B ear drops. In the US, products containing benzocaine for oral application are contraindicated in children younger than two years old. In the European Union, the contraindication applies to children under 12 years of age.
benzocaine vs lidocaine
lidocaine is a stronger, yet equally effective, local anesthetic than Benzocaine and its effects last for approximately 90 minutes. Benzocaine is considered to be less severe in nature and its effects last for around ten minutes from the time of application.
Benzocaine is a topical anesthetic contained in some marketed over-the-counter (OTC) oral drug products intended to relieve pain from a variety of conditions such as sore throats, canker sores, and irritation of the mouth and gums.
how much benzocaine is dangerous
Use over-the-counter (OTC) benzocaine products in adults and children 2 years and older sparingly and only as needed. Do not use the product more than four times a day.
benzocaine side effects
- Bluish-colored lips, fingernails, or palms.
- difficulty breathing.
- dizziness or lightheadedness.
- high fever.
- rapid heart rate.
- worsening of pain, redness, swelling, or irritation in or around the mouth.
benzocaine melting point