Propionyl chloride
CAS 79-03-8
MF:C3H5ClO
It is used as a propionylation reagent in organic synthesis and is an intermediate for the preparation of various propionic acid derivatives, such as propiophenone, etc.; it is used in the production of pesticide propanil; in the pharmaceutical industry, it is used in the production of antiepileptic drugs dimension, Cholesterol, anti-adrenergic drug methoxyamine hydrochloride, etc.
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Description
Propionyl chloride CAS 79-03-8 Product Description
| Product Name: | Propionyl chloride |
| Synonyms: | Propanoylchlorid;chloro anhydride of propionic acid;Propionchloride;n-propanoyl chloride;MFCD00000745;EINECS 201-170-0;Propionyl cloride;Propionic acid chloride;Propionic chloride;Propionylchloride;Propionylchlorid;Propionyl chloride;propionyl;Propanoyl chloride |
| CAS NO: | 79-03-8 |
| Molecular Weight: | 92.52 |
| Molecular Formula: | C3H5ClO |
| Boiling Point: | 77-79 °C (lit.) |
| Melting point: | -94 °C |
| Density: | 1.059 g/mL at 25 °C (lit.) |
| Appearance: | Clear liquid |
| Purity: | >98% |
| Solubility: | Water solubility: REACTS |
| Storage: | Store below +30°C |
propionyl chloride uses
Propionyl chloride is used as an intermediate in the production of agrochemicals and pharmaceuticals. It serves as an intermediate for dyes, textile auxiliaries and peroxide compounds. It acts as a crop protecting agent.
propionyl chloride synthesis
Propionyl chloride is synthesized by reacting propionic acid with phosphorus trichloride at 40-50°C for 1h, cooling, standing, separating and distilling to obtain the product.
CH3CH2COOH+PCl3→CH3CH2COCl+HOPCl2
Propionyl chloride is produced industrially by treatment of propionic acid with phosgene or thionyl chloride. The reaction occurs at ca. 50°C in the liquid phase in the presence of dialkylformamides. The product is then separated by distillation.
CH3CH2CO2H + COCl2 → CH3CH2COCl + HCl + CO2
Propionyl chloride can also be obtained by the reaction of propionic acid with PCl5.
propionyl chloride structure
Propionyl chloride (also propanoyl chloride) is the organic compound with the formula CH3CH2C(O)Cl. It is the acyl chloride derivative of propionic acid. It undergoes the characteristic reactions of acyl chlorides. It is a colorless, corrosive, volatile liquid.
propionyl chloride reaction with water
Propionyl chloride reacts vigorously or violently with water to form propionic acid and hydrochloric acid.
propionyl chloride solubility
Water solubility: REACTS
propionyl chloride melting point
-94 °C
propionyl chloride density
1.059 g/mL at 25 °C (lit.)
propionyl chloride cas no
C3H5ClO
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