CompoundsOrganic Compounds2-Bromo-1-Phenyl-1-Butanone CAS 1451-83-8

SKU: WGP-1451-83-8

2-Bromo-1-Phenyl-1-Butanone

CAS 1451-83-8

Molecular Formula: C10H11BrO
Molecular Weight: 227.1
MOQ:1KG
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2-Bromo-1-Phenyl-1-Butanone CAS 1451-83-8 Product Information

Product Name: 2-Bromo-1-Phenyl-1-Butanone
Synonyms: 2-bromo-3-methylpropiophenone;2-bromo-1-(3-methylphenyl)propan-1-one;2-Bromo-1-m-tolyl-propan-1-one;2-Bromo-1-Phenyl-1-Butanone / 2-bromo-1-(3-methylphenyl)propan-1-one;1-Propanone, 2-bromo-1-(3-methylphenyl)-;2-Bromo-1-Phenyl-1-Butanone;2-Bromo-1-Phenyl-1-Butanone CAS 1451-83-8;2-Brom-3′-methylpropiophenon
CAS NO: 1451-83-8
Molecular Weight: 227.1
Molecular Formula: C10H11BrO
Boiling Point: 134-135 °C(Press: 8 Torr)
Density: 1.357±0.06 g/cm3(Predicted)
Appearance: White powder fine
Purity: >98%
Storage: no restrictions.

What is 2-Bromo-1-Phenyl-1-Butanone?

2-Bromo-1-Phenyl-1-Butanone, identified by the CAS NO. 1451-83-8, is an organic molecule that serves as a key component in chemical synthesis. Below are few crucial aspects regarding this compound:

1. Chemical Structure: The chemical formula for 2-Bromo-1-Phenyl-1-Butanone is C10H11BrO. The compound consists of a phenyl group (C6H5) connected to a butanone backbone, with a bromine atom (Br) located at the 2-position and a ketone functional group (C=O) located at the 1-position.

2. Physical Properties: 

  • Appearance: Generally, it is a transparent to light yellow liquid or solid.
  • Solubility: Typically, it exhibits solubility in organic solvents such as ethanol, methanol, and chloroform.

3. Synthesis: This molecule can be produced by adding bromine or N-bromosuccinimide (NBS) to 1-Phenyl-1-butanone, with the use of a catalyst or under UV light.

4. Applications:

  • Pharmaceuticals: It is frequently employed as an intermediary in the manufacture of medicinal drugs. The structure of this compound permits additional chemical alterations, resulting in the creation of a diverse range of pharmacologically active compounds.
  • Chemical Synthesis: In the field of organic chemistry, it functions as a fundamental component for the creation of more intricate molecules. The compound’s reactivity, namely due to the presence of the bromine and ketone functional groups, renders it valuable in a range of chemical reactions, such as nucleophilic substitution and coupling reactions.
  • Research: In research and development laboratories, it is employed to investigate novel synthetic pathways and to create new materials and chemicals.

5. Reactivity:

  • Nucleophilic Substitution: The bromine atom can undergo substitution reactions with different nucleophiles, allowing for the formation of a diverse array of derivatives.
  • Enolate Chemistry: The ketone group has the ability to generate enolates, which can subsequently engage in diverse carbon-carbon bond-forming processes.

6. Safety and Handling:

Due to its nature as a chemical intermediate, it is imperative to use caution when handling 2-Bromo-1-Phenyl-1-Butanone. Exposure to this substance through inhalation, ingestion, or contact with the skin and eyes can have severe effects. It is essential to utilise appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats, while handling this chemical. Additionally, it is imperative to work in a well-ventilated location or under a fume hood.

2-Bromo-1-Phenyl-1-Butanone is a highly useful substance in organic synthesis, especially in the pharmaceutical sector, because of its high reactivity and ability to create a wide range of chemical compounds.

Transit time You will normally receive your parcel within 7-15 working days after shipment (this may be delayed in special circumstances, such as Chinese New Year).
Receiving method Generally we will send the goods by courier or special line, of course, if the goods themselves in the local warehouse have goods, also support self-pickup, depending on the circumstances.
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Delivery Method WGP will ship via courier companies such as DHL, FedEx, UPS, TNT or EMS.
About After Sales Within 7 days of your receipt of the goods if you find any problems with the goods (broken packaging, less hair, etc.) please feel free to contact our sales, we will help you deal with it in time.

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