СоединенияАктивные ингредиентыEtomidate CAS 33125-97-2

Этомидат CAS 33125-97-2  Информация о товаре

what is etomidate

Etomidate is a type of medication called a general anesthetic. It works by affecting the brain and nervous system to cause loss of consciousness and prevent pain during surgery or other procedures. Etomidate is given as an injection into a vein by a doctor or nurse. The dosage of etomidate depends on various factors, such as the patient’s age, weight, medical condition, and response to the medication. Etomidate has some advantages and disadvantages compared to other anesthetics, such as propofol. Your doctor or anesthesiologist will explain more about etomidate and its possible side effects before giving it to you.

etomidate dose

Etomidate is a type of medication called a general anesthetic. It works by affecting the brain and nervous system to cause loss of consciousness and prevent pain during surgery or other procedures. Etomidate is given as an injection into a vein by a doctor or nurse. The dosage of etomidate depends on various factors, such as the patient’s age, weight, medical condition, and response to the medication. The usual adult dose for etomidate is 0.2 to 0.6 mg/kg given over 30 to 60 seconds. The usual pediatric dose for etomidate is 0.3 mg/kg given over 30 to 60 seconds. Etomidate should be used with caution in patients with heart problems, low blood pressure, adrenal insufficiency, or seizures.

etomidate mechanism of action

Etomidate works by binding to and activating a type of receptor in the brain and nervous system called the gamma-aminobutyric acid type A (GABA-A) receptor. This receptor is responsible for inhibiting the activity of nerve cells and producing sedation, relaxation, and anesthesia. By enhancing the effect of GABA-A receptors, etomidate reduces the transmission of pain signals and induces loss of consciousness. Etomidate also inhibits the production of a hormone called cortisol by the adrenal glands. Cortisol is involved in the body’s response to stress and inflammation. By lowering cortisol levels, etomidate may reduce the risk of complications during surgery or trauma. However, this effect may also cause side effects such as low blood pressure, nausea, vomiting, and adrenal insufficiency.

etomidate side effects

Etomidate may cause some side effects, such as:

• Low blood pressure
• Slow or irregular heartbeat
• Breathing problems
• Nausea and vomiting
• Involuntary muscle movements or twitching
• Pain or burning at the injection site
• Headache
• Dizziness
• Adrenal insufficiency (a condition where the adrenal glands do not produce enough hormones)
• Allergic reactions (such as rash, itching, swelling, or difficulty breathing)