Introduction
As an excellent supplier of chemical raw materials in China, WGP is committed to providing high-quality products as well as considerate services to global sellers. So far, our products are exported to North America, Europe, Australia and some countries in Latin America.
WGP’s products have been well received by our customers, and WGP will continue to provide high-quality products and considerate service to our global customers. Next is the introduction of our popular product P2NP.
What is the CAS number 705 60 2?
CAS No. 705-60-2 corresponds to trans-β-methyl-β-nitrostyrene, a light yellow crystalline solid with the molecular formula C9H9NO2 and molecular weight of 163.17 g/mol.It is also known as phenyl-2-nitropropropene (P2NP), and is used in the pharmaceutical industry to make the drug Adderall, which is used in the treatment of ADHD and episodic somnolence. amphetamine mixture used to treat ADHD and episodic sleep disorders. P2NP and other similar nitrostyrenes are also used in the clandestine manufacture of amphetamine-type drugs and are classified as drug precursors in many countries.
p2np Molecular Structure
The molecular structure of Phenyl-2-nitropropene (P2NP) is shown below:
H NO2
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H-C=C-CH-Ph
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H H
P2NP is a light yellow crystalline solid with a distinctive odour 1 . Its molecular formula is C9H9NO2 and its molecular weight is 163.17 g/mol.
What is phenyl 2 Nitropropene used for?
- Phenyl-2-nitropropene (P2NP) is used in the pharmaceutical industry to make the drug Adderall, a mixture of amphetamines used to treat ADHD and episodic sleeping sickness.
- P2NP is a stable compound with aromatic and alkyl substituents that can act as a Michael receptor, making it useful in organic synthesis and medicinal chemistry. It has potential applications in drug synthesis, herbicidal properties and antimicrobial activity.
P2NP synthesis
The synthesis of P2NP involves the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst such as n-butylamine. The reaction proceeds through the formation of β-nitroalcohols, which are subsequently dehydrated to produce nitroolefins. The following is a step-by-step procedure for the synthesis of P2NP:
- Mix 15 mL of benzaldehyde and 10 mL of nitroethane in a 100 mL round bottom flask.
- 1.5 g of anhydrous ammonium acetate and 1.5 mL of n-butylamine are added to the flask.
- Stir the mixture at room temperature for 24 hours.
- The reaction mixture is poured into a dispensing funnel and extracted with 50 mL of ether.
- The organic layer was washed with 50 mL of water and dried over anhydrous magnesium sulfate.
- Filter the solution and evaporate the solvent under reduced pressure.
- The crude product was recrystallised from ethanol to give pure P2NP.
P2NP Safety Measures and Regulatory Compliance
As with any compound, it is important to handle P2NP with care and follow proper safety measures. The Occupational Safety and Health Administration (OSHA) has set the Permissible Exposure Limit (PEL) for P2NP in the workplace at 0.05 mg/m3. P2NP is also classified as a hazardous material by the U.S. Department of Transportation (DOT) and must be properly labelled and packaged for transport.
In addition, regulatory compliance is an important aspect of dealing with P2NP. Companies that manufacture, distribute, or use P2NP must comply with a variety of regulations and guidelines established by government agencies such as the Environmental Protection Agency (EPA), the Food and Drug Administration (FDA), and the Drug Enforcement Administration (DEA). These regulations are designed to ensure the safe handling, storage, and disposal of P2NP and other hazardous materials and to prevent their misuse in the production of illegal drugs.
Conclusion
As we learnt about P2NP (CAS 705-60-2), we witnessed its unique properties, applications and safety considerations.P2NP plays an important role in different scientific and industrial fields.
FAQs
- How do I securely handle P2NP?
A: Adherence to the recommended security protocols is essential for the secure handling of P2NP.
2. Where can I find suppliers of P2NP?
A: WGP, as an excellent supplier of chemical raw materials in China, is now selling P2NP.If you want to know more about P2NP, no matter it is the product information or product price, shipping, packaging and other related information, please feel free to contact us. Our sales will offer you the best price solution about P2NP. If you have any idea about packaging of P2NP, please contact us, we support customized packaging service. No matter what, WGP will be your best choice, please trust us.
3. Do you have any other products you recommend?
Of course, if you want to buy something else in the near future WGP will meet all your needs. Below is the information of the products we are selling, please check it out:
BMK Glycidic Acid CAS 5449-12-7
2-BROMO-1-PHENYL-PENTAN-1-ONE CAS 49851-31-2
