1. What is YK-11 CAS 1370003-76-1?
YK-11 CAS 1370003-76-1 is a new synthetic steroid based on 5-alpha-dihydrotestosterone ( DHT ), a natural hormone in the human body. DHT is a more potent form of testosterone that targets androgen receptors in the prostate, sex organs, hair, and liver.
YK-11 is gaining interest from bodybuilders, who believe it can help them quickly build muscle with minimal side effects- a belief not founded in the available science. The YK molecule has more in common with steroids than SARMs, although it’s often mistakenly labelled as a non-steroidal SARM.
YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM). It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR.
The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard. It has been investigated as a potential treatment for sepsis-induced muscle wasting in animal studies.
2. How does YK-11 work?
The YK-11 s method of action is similar to the one of DHT in the body. Simply explained, YK-11 binds to the androgen receptors. By doing so, the levels of anabolic factors in the body are increased; hence the buildup of strong muscle mass happens.
This allows YK-11 to not only promote muscle growth but to also promote muscle retention, which is very important during a cycle. But this is not the only method of action when it comes to YK-11.
According to the studies that have been performed so far, YK-11 is also able to increase the follistatin levels in the body, thus inhibiting myostatin. Myostatin inhibition is not something that many SARMs are able to make happen. This is one of the many things that makes YK-11 special.
Follistatin is a protein that is naturally produced by the human body. It takes part in many important body functions, including metabolism control, and muscle growth, and it can even boost fertility.
Myostatin, on the other hand, is another naturally-occurring protein in the body, one that is responsible for inhibiting myogenesis-muscle cell growth and degeneration.
By inhibiting myostatin and increasing follistatin, YK-11 works to make sure that your muscles are rapidly growing. In addition, the recovery time will be shorter, and you will be able to engage in intensive sessions at the gym for longer periods of time. Forget all about muscle soreness, thanks to YK-11.
3. YK-11 side effects and benefits
- YK-11 benefits
YK-11 is considered to be extremely helpful and effective as a part of the bodybuilding process. Multiple beneficial effects are expected to occur shortly after the use of YK-11 has started. In the following, we will go over the supposed benefits of YK-11.
- YK-11 Rapid muscle growth
The most obvious benefit of using YK-11 daily is rapid muscle growth. If you want to grow strong and toned muscles, then YK-11 is the one that you need to choose. The muscle tissues seem to have high anabolic effects when exposed to YK-11, with these effects being much more intense as compared to the effects achieved with the exposure of muscle tissues to DHT.
Here, a major influence also has myostatin inhibition and the increase of follistatin levels. It is thanks to these two events that YK-11 can further, promote muscle mass growth.
- YK-11 Increased muscle strength
The goal of YK-11 is not to pump your muscles but also to make them stronger. Through the production of follistatin, YK-11 works to strengthen your muscles, making them stronger than ever. Soon you will be able to lift more than ever before, all thanks to the daily use of YK-11!
- YK-11 Enhanced bone health
Sex hormones, with testosterone being one of them, play a major role in the strengthening of the bones, thus enhancing bone health. By binding to the androgen receptors inside the bone tissue, YK-11 can work to strengthen the bones, similar to how steroids and the rest of the SARMs work.
A study published in the Biological & Pharmaceutical Bulletin investigated the effects of YK-11 on activated PKB (protein kinase B). PKB, when activated, is sending signals to the bones, thus promoting bone growth. The results found that YK-11 is able to activate PKB, hence promoting bone growth and strength.
- YK-11 Visible fat loss
Fat loss is one of the major advantages that YK-11 has to offer over most other SARMs and steroids. YK-11 focuses on replacing any excess fat mass with solid, strong muscle mass – one that you can be proud of.
Additional benefits include enhanced libido, improved athletic performance, better sleep, increased endurance, muscle maintenance after the cycle, no water retention, etc. Users report on feeling better overall, being in a better mood, and having a greater motivation to work hard on their bodies.
- YK-11 Side Effects
Of all the SARMS out there, YK-11 is the one with the least information available. This means that there isn’t any clinical data available to support claims being made about the use of this compound and its side effects. This makes it extremely unsafe, meaning you should not be using it.
We have done our research and have gone through several user logs that have written down their experience.
Users have reported the following side effects:
- Hormone suppression
- Stomach issues
- Hair loss
- Increased aggression
- Joint pain
4. Where to buy YK-11?
YK-11 CAS 1370003-76-1 is available online from different YK-11 manufacturers. Most users of YK-11 buy from different websites, some for retail or wholesale purposes. Verify the legitimacy of every YK-11 manufacturer using outlined state laws before purchase.
We are one of the best manufacturers in China, we can offer you YK-11 CAS 1370003-76-1 with Top Quality and High Purity. You can also browse our website: http://www.whwingroup.com or platform: https://www.chemicalbook.com/manufacturer/ExhibitionBooth464/.
- Kanno Y, Hikosaka R, Zhang SY, Inoue Y, Nakahama T, Kato K, Yamaguchi A, Tominaga N, Kohra S, Arizono K, Inouye Y (2011).
- Kanno Y, Ota R, Someya K, Kusakabe T, Kato K, Inouye Y (2013). “Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression”. Biological & Pharmaceutical Bulletin. 36 (9): 1460C5.
- Lee, Su Jin; Gharbi, Amal; Shin, Joo Eun; Jung, In Duk; Park, Yeong Min (2021-03-05). “Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis”. Biochemical and Biophysical Research Communications. 543: 1C7