Testosterone Undecanoate
CAS:5949-44-0
MF: C30H48O3
Testosterone Undecanoate is the undecanoate ester form of the androgen testosterone, with gonadotropin-secretory inhibiting and hormone replacement activity. As testosterone inhibits the secretion of gonadotropins from the pituitary gland, administration of testosterone decreases the secretion of luteinizing hormone (LH). By inhibiting LH secretion, the growth of Leydig cells, which are normally stimulated by LH to produce testosterone, may be suppressed. In addition, this agent promotes the maintenance of male sex characteristics and can be used for testosterone replacement in hypogonadal males.
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Description
Testosterone Undecanoate CAS 5949-44-0 Product Information
Product Name: | Testosterone Undecanoate |
Synonyms: | TESTOSTERONE UNDECANOATE;TESTOSTERONE UNDECANOILATE;17-beta-hydroxy-5-alpha-androstan-3-onundecanoate;testosterone,undecanoate(ester);andriol;4-ANDROSTEN-17BETA-OL-3-ONE 17-UNDECANOATE;4-ANDROSTEN-17-BETA-OL-3-ONE UNDECANOATE;17-[(1-oxoundecyl)oxy]-androst-4-en-3-one |
CAS NO: | 5949-44-0 |
Molecular Weight: | 456.7 |
Molecular Formula: | C30H48O3 |
Boiling Point: | 550.7±50.0 °C at 760 mmHg |
Melting point: | 39-42 °C(lit.) |
Density: | 1.0±0.1 g/cm3 |
Appearance: | White Solid |
Applications: | It is available as an intramuscular injection and as an oral capsule, and is indicated for treatment of testosterone deficiency. It should be noted that testosterone undecanoate is only indicated for treatment of hypogonadal conditions with structural or genetic etiologies and should not be used to manage “age-related hypogonadism”. |
Solubility: | DMSO : 10 mg/mL (21.90 mM; Need ultrasonic and warming) |
Storage: | Controlled Substance, -20°C Freezer |
testosterone undecanoate benefits
It helps the body to develop and maintain male sexual characteristics (masculinity), such as a deep voice and body hair. It also helps to maintain muscle and prevent bone loss, and is needed for natural sexual ability/desire. This medication should not be used in women.
testosterone undecanoate dosage
Testosterone undecanoate is used in androgen replacement therapy. It is specifically approved only for the treatment of hypogonadism. As an intramuscular injection, it is administered at a dosage of 1,000 mg once every 12 weeks Conversely, oral testosterone undecanoate must be taken two or three times a day with food.
testosterone undecanoate vs cypionate
The testosterone undecanoate group has a higher percentage of men with newly diagnosed erectile dysfunction and obesity at follow-up, whereas the testosterone cypionate group had a higher percentage of men with diagnosed hypertension, congestive heart failure and chronic pain.
testosterone undecanoate half life
Testosterone undecanoate has a very long elimination half-life and mean residence time when given as a depot intramuscular injection. Its elimination half-life is 20.9 days and its mean residence time is 34.9 days in tea seed oil, while its elimination half-life is 33.9 days and its mean residence time is 36.0 days in castor oil.These values are substantially longer than those of testosterone enanthate (which, in castor oil, has values of 4.5 days and 8.5 days, respectively). Testosterone undecanoate is administered via intramuscular injection once every three months or so.
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Color | White |
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Form | Powder |
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