PeptidesSynthetic PeptidesTerlipressin CAS NO 14636-12-5

SKU: WGP-14636-12-5

CAS 14636-12-5
MF: C54H78N16O17S2
FW: 1287.433

Terlipressin is a synthetic peptide analog of vasopressin, also known as 1-deamino-8-D-arginine vasopressin (DDAVP)

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  • Additional information


Terlipressin CAS NO 14636-12-5 product information

CAS NO: 14636-12-5
Product Name: Terlipressin Acetate
Synonyms: [N-α-Triglycyl-8-lysine]-vasopressin;130: PN: WO2010033207 SEQID: 171 claiMed protein;1-Triglycyl-8-lysine Vasopressin;Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin;Nα-Glycyl-glycyl-glycyl-lysine-vasopressin;Nα-Glycylglycylglycyl-vasopressin;Nα-Gly-Gly-Gly-8-Lys-vasopressin;Terlipressin, Terlipressine, Terlipressina, Terlipressinum
Molecular Formula: C54H78N16O17S2
Formula Weight: 1287.433
EINECS: 238-680-8
Boiling point: 1824.0±65.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
Appearance: Solid powder
Purity: >98%
Storage: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Solubility:  Soluble in DMSO, not in water
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

What is terlipressin used for?

Terlipressin is a modified form of vasopressin where the amino acid phenylalanine at the third position is replaced by lysine. This modification increases the half-life of the molecule, allowing for a longer duration of action.

Terlipressin is a vasoactive hormone that acts on specific receptors in the blood vessels, mainly the V1 receptors. By binding to these receptors, it constricts blood vessels and increases blood pressure. This vasoconstrictive effect is beneficial in the treatment of conditions such as variceal bleeding, where it helps to reduce bleeding by constricting the dilated blood vessels.

The chemical synthesis of terlipressin involves solid-phase peptide synthesis (SPPS) techniques. Sequential addition of protected amino acids on a solid support, followed by deprotection and cleavage, leads to the synthesis of the peptide. Purification techniques such as high-performance liquid chromatography (HPLC) are used to obtain the final product in a pure form.

In pharmaceutical preparations, terlipressin is often formulated as a lyophilized powder for reconstitution before administration. It can be administered intravenously or subcutaneously, depending on the specific indication and formulation.

Chemists and researchers continue to study terlipressin and explore its therapeutic applications in various medical conditions. The understanding of its chemical properties and structure-activity relationship helps in optimizing its pharmacological properties, improving its stability, and developing novel formulations for enhanced efficacy and patient convenience.


WGP Strength

WGP is a technological enterprise engaged in the R&D, production and marketing of raw chemical materials. Whwingroup offers a broad range of specialty chemicals and customized synthesis services to a range of biochemical industries.



Additional information




Crystal powder


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