CAS 196078-30-5
MF: C173H273N51O56S2
Pramlintide acetate is an amlyinomimetic, a functional analog of the naturally occurring pancreatic hormone amylin.
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Description
Pramlintide Acetate CAS 196078-30-5 Product Information
CAS NO: | 196078-30-5 |
Product Name: | Pramlintide acetate |
Synonyms: | AMYLIN (HUMAN), 25-L-PROLINE-28-L-PROLINE-29-L-PROLINE-, ACETATE (SALT), HYDRATE;pramlintide acetate;pramlintide acetate hydrate;25-L-Proline-28-L-proline-29-L-proline-aMylin (huMan) Acetate Hydrate;AC-137 Acetate Hydrate, SyMlin Acetate Hydrate;Tripo-aMylin Acetate Hydrate;Pramlintide Acetate, Amylin Rat;Pramlintide acetate fandachem |
Molecular Formula: | C173H273N51O56S2 |
Molecular Weight: | 4027.46 |
Melting point: | >175°C (dec.) |
Solubility: | Acetic Acid (Slightly), DMSO (Slightly) |
Storage: | Refrigerator |
Appearance: | White to Off-White Solid |
Purity: | >98% |
Description:
Pramlintide acetate is an amlyinomimetic, a functional analog of the naturally occurring pancreatic hormone amylin. Amylin is active in many gastrointestinal and glucose dynamic systems, and by mimicking its activity, pramlintide improves blood glucose by regulating gastric emptying rate, preventing postprandial glucagon levels rise and by increasing satiety control, thereby reducing caloric intake and increasing weight loss. There appear to be at least three distinct receptor complexes that bind amylin with high affinity. All three complexes contain the core calcitonin receptor, and one of three receptor activity-modifying proteins, RAMP1, RAMP2, or RAMP3.
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Additional information
Color | White to offwhite |
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Form | Crystal powder |
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