Plecanatide CAS NO 467426-54-6

SKU: WGP-467426-54-6

CAS 467426-54-6
MF: C65H104N18O26S4
FW: 1681.89
  • Description
  • Additional information

Description

CAS NO: 467426-54-6
Product Name: Plecanatide
Synonyms: Plecanatide;ASN-ASP-GLU-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BOND CYS1&CYS3,CYS2&CYS4);Plecanatide Impurtiy;L-Leucine, L-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12),(7→15)-bis(disulfide);Plecanatide fandachem;Plecanatide impurity;Plecanatide USP/EP/BP;Prikanatide
Molecular Formula: C65H104N18O26S4
Molecular Weight: 1681.89
Boiling point: 2120.0±65.0 °C(Predicted)
Density: 1.47±0.1 g/cm3(Predicted)
Appearance: Solid powder
Purity: >98%
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO

 

Description:

Plecanatide is an analog of uroguanylin, an orally active guanylate cyclase-C (GC-C) receptor agonist, in T84 cells, EC50 value 190 nM. Plecanatide can be used in the study of chronic idiopathic constipation and has anti-inflammatory activity in mouse colitis models.

Applications:

Plecanatide is used in the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation. It works as a laxative by drawing water in to the gastrointestinal tract thereby softening stool and encouraging its natural passage.

Additional information

Color

White

Form

Crystal powder

    Reviews

    There are no reviews yet.

    Be the first to review “Plecanatide CAS NO 467426-54-6”