CAS 74381-53-6
MF: C61H88N16O14
FW: 1269.47
- Description
- Additional information
Description
| CAS NO: | 74381-53-6 |
| Chemical Name: | Leuprorelin acetate |
| Synonyms: | lupron;tap-144;Prostap;Procrin;TPA-144;DC-2-269;tap-144-sr;LEUPROLIDE;Abbott 43818;Procren Depot |
| Molecular Formula: | C61H88N16O14 |
| Formula Weight: | 1269.47 |
| Melting Point: | 150-155°C |
| Storage Temp: | -20°C |
| Purity: | ≥98% |
| Formulation: | A crystalline solid |
| Solubility: | DMF: 30 mg/ml
DMSO: 30 mg/ml Ethanol: 0.25 mg/ml PBS (pH 7.2): 10 mg/ml |
| Shipping: | Room Temperature in continental US; may vary elsewhere |
Description:
Leuprorelin is a synthetic gonadotropin-releasing hormone (GnRH) receptor agonist. It is a long-acting agent that, after an initial increase in sex hormone levels, decreases the level of circulating gonadotropins and sex hormones. Formulations containing leuprorelin have been used in the treatment of hormone-dependent prostate and breast cancers, endometriosis, and precocious puberty.
Chemical Properties:
Fluffy Solid
Uses:
Leuprolide acetate USP (Leupron) is used to treat Prostatic carcinoma.
Definition:
ChEBI: An acetate salt obtained by combining the nonapeptide leuprolide with acetic acid. A long lasting GnRH analog, LH-Rh agonist. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant for the t eatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
Additional information
| Color | White |
|---|---|
| Form | Crystal powder |
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