Letrozole Femara CAS 112809-51-5

SKU: WGP-112809-51-5
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Cas  112809-51-5
MF:  C₁₇H₁₁N₅
MW: 285.3
  • Description
  • Additional information

Description

Chemical Name Letrozole
Synonyms 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile; 4-[1-(4-Cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile; CGS 20267; Femara; Lerozole; Letrazole;
CAS Number 112809-51-5
Molecular Formula C₁₇H₁₁N₅
Appearance White to Off-White Solid
Melting Point 181-186°C
Molecular Weight 285.3
Storage -20°C Freezer
Solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic.

Description:

Letrozole is an inhibitor of aromatase that prevents the formation of estrogens; it is clinically used to treat hormone-responsive breast cancer and infertility and to terminate pregnancy. Letrozole exhibits anticancer chemotherapeutic and anti-estrogenic activities. In vivo, letrozole increases secretion of luteinizing hormone (LH), lengthens the follicular dominance period, and delays subsequent follicular waves.

Please note that all purities are given on a dry basis. The purity does not include water or solvent that may be present. These quantities will be listed separately on the COA when applicable

Additional information

Color

White

Form

Powder

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