Letrozole Femara CAS 112809-51-5

SKU: WGP-112809-51-5


Cas  112809-51-5
MF:  C₁₇H₁₁N₅
MW: 285.3
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Chemical Name Letrozole
Synonyms 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile; 4-[1-(4-Cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile; CGS 20267; Femara; Lerozole; Letrazole;
CAS Number 112809-51-5
Molecular Formula C₁₇H₁₁N₅
Appearance White to Off-White Solid
Melting Point 181-186°C
Molecular Weight 285.3
Storage -20°C Freezer
Solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic.


Letrozole is an inhibitor of aromatase that prevents the formation of estrogens; it is clinically used to treat hormone-responsive breast cancer and infertility and to terminate pregnancy. Letrozole exhibits anticancer chemotherapeutic and anti-estrogenic activities. In vivo, letrozole increases secretion of luteinizing hormone (LH), lengthens the follicular dominance period, and delays subsequent follicular waves.

Please note that all purities are given on a dry basis. The purity does not include water or solvent that may be present. These quantities will be listed separately on the COA when applicable

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