Clomiphene citrate
CAS: 50-41-9
MF: C32H36ClNO8
Selective estrogen receptor modulator, which acts by inhibiting the action of estrogen on the pituitary. Clomiphene Citrate is an activator of PKC and Gonad-stimulating principle.
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Description
Clomiphene citrate CAS 50-41-9 Product Information
| Product Name: | Clomiphene Citrate |
| Synonyms: | {2-[4-(2-chloro-1,2-diphenylvinyl)phenoxy]ethyl}diethylamine 2-hydroxy-1,2,3-propanetricarboxylate (salt);2-(4-(2-Chloro-1,2-diphenylvinyl)phenoxy)-N,N-diethylethanaMine 2-hydroxypropane-1,2,3-tricarboxylate;CloMiphene Cit;2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethyl-ethanamine, 2-hydroxy-1,2,3-propanetricarboxylate (1:1);Clometeu Citrate;Clomiphene,ClomifeneCltrate;2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)-triethylamincitrate(1:1);2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylaminecitrate(1:1) |
| CAS NO: | 50-41-9 |
| Molecular Weight: | 598.08 |
| Molecular Formula: | C32H36ClNO8 |
| Boiling Point: | 509ºC at 760 mmHg |
| Melting point: | 116.5-118°C |
| Applications: | 1.0±0.1 g/cm3 |
| Appearance: | White to Off-White Crystalline Solid |
| Applications: | Clomiphene citrate is used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation. Clomiphene citrate(CC )has also been employed for ovarian stimulation in ovulating women, mainly for idiopathic (unexplained) infertility and often combined with IUI. |
| Solubility: | Slightly soluble in water, sparingly soluble in ethanol (96 per cent). |
| Storage: | 2-8°C |
clomiphene citrate side effects
Stomach upset, bloating, abdominal/pelvic fullness, flushing (“hot flashes”), breast tenderness, headache, or dizziness may occur. Tell your doctor right away if you have any serious side effects, including: abnormal vaginal bleeding, mental/mood changes.
What is clomiphene citrate?
Clomiphene is a selective estrogen receptor modulator that impairs the activation of estrogen receptors (ERs) by 17β-estradiol. It potently binds both ERα and ERβ (Ki = 0.9 and 1.2 nM, respectively). Clomiphene enhances the release of gonadotropin-releasing hormone, stimulating the release of follicle-stimulating hormone and luteinizing hormone, culminating in ovulation.
clomiphene citrate men
In males, clomiphene citrate increases levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are important for fertility and are present in both males and females. LH encourages the release of testosterone in males.
clomiphene citrate for women
Clomiphene improves the chances of becoming pregnant for most women who ovulate irregularly, and it carries a low risk of dangerous side effects. In addition to anovulation, clomiphene is also administered in conjunction with intrauterine insemination in unexplained infertility.
Additional information
| Color | White |
|---|---|
| Form | Crystal powder |
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