Exemestane
CAS:107868-30-4
MF: C20H24O2
Exemestane was launched in US and other countries for the treatment of estrogendependent tumors and postmenopausal breast cancer. It is a novel steroidal compound structurally related to the natural substrate for the biosynthesis of estrogen, androstanedione, and can be synthesized by methylidenation of androsta-1, 4-dien- 17beta-ol-3-one in 6 position then oxidation of the alcohol function. Exemestane is an irreversible inactivator of the aromatase enzyme system, so inducing in vivo a dose-related sustained suppression of serum estrogen and minimal endocrine activity.
- Description
- Additional information
Description
Exemestane CAS 107868-30-4 Product Information
Product Name: | Exemestane |
Synonyms: | ExeMestane (USP);ExeMestane(AroMasin);1,4-Androstadien-3,17-dione-6-Methylene-d2;(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971 |
CAS NO: | 107868-30-4 |
Molecular Weight: | 296.4 |
Molecular Formula: | C20H24O2 |
Boiling Point: | 453.7±45.0 °C(Predicted) |
Melting point: | 155.13°C |
Density: | 1.13±0.1 g/cm3(Predicted) |
Appearance: | white to off-white powder |
Applications: | Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.. |
Solubility: | DMSO: ≥20mg/mL |
Storage: | 2-8°C |
Keywords
exemestane
exemestane bodybuilding
exemestane side effects
exemestane dosage on cycle
coming off exemestane
exemestane hair loss
exemestane pct
exemestane and uterine cancer
exemestane for sale
buy exemestane
exemestane side effects weight gain
letrozole vs exemestane bodybuilding
exemestane and alcohol
exemestane only
exemestane steroids
anastrozole vs exemestane
exemestane breast cancer
exemestane cost
exemestane mechanism of action
buy exemestane online
exemestane vs letrozole
exemestane bnf
exemestane warnings
exemestane and sun exposure
exemestane pronunciation
what are the long term side effects of exemestane
Additional information
Color | White to offwhite |
---|---|
Form | Powder |
Reviews
There are no reviews yet.