Local AnestheticDimethocaine Hydrochloride CAS 553-63-9

SKU: WGP-553-63-9

 Dimethocaine Hydrochloride

MF: C16H26N2O2.ClH

Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.

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Dimethocaine Hydrochloride CAS 553-63-9 Product Information

Product Name:  Dimethocaine Hydrochloride
Synonyms: Larocaine hydrochloride;Dimethocaine hydrochloride;1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 1-(4-aminobenzoate), hydrochloride (1:1);Larocaine HCl;3-(Diethylamino)-2,2-dimethyl-1-propanol 4-aminobenzoate hydrochloride;3-(diethylaMino)-2,2-diMethyl-1-Propanol 1-(4-aMinobenzoate) hydrochloride;1-AMinobenzoyl-2,2-diMethyl-3-diethylaMinopropanol Hydrochloride;3-DiethylaMino-2,2-diMethylpropyl p-aMinobenzoate Hydrochloride
CAS NO:  553-63-9
Molecular Weight: 314.854
Molecular Formula: C16H26N2O2.ClH
Boiling Point: 403.5ºC at 760 mmHg
Melting point: 195-196℃
Density: 1.035g/cm3
Appearance: White to Pale Beige Solid
solubility DMSO (Slightly), Water (Slightly)

Dimethocaine Hydrochloride CAS 553-63-9 uses

Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson’s disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy.

What is Dimethocaine

Dimethocaine, also known as DMC or larocaine, is a compound with a stimulatory effect. This effect resembles that of cocaine, although dimethocaine appears to be less potent. Just like cocaine, dimethocaine is addictive due to its stimulation of the reward pathway in the brain. However, dimethocaine is a legal cocaine replacement in some countries and is even listed by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) under the category “synthetic cocaine derivatives”

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