Benzocaine hydrochloride is a salt modification of benzocaine, formed when benzocaine is complexed with hydrochloric acid. Compared to benzocaine, benzocaine hydrochloride is more water soluble, making it more appropriate for oral administration.
Benzocaine hydrochloride CAS 23239-88-5 Product Information
|Product Name:||Benzocaine hydrochloride|
|Synonyms:||Benzoic acid, 4-amino-, ethyl ester, hydrochloride;4-Amino-benzoesaeure-aethylester,Hydrochlorid;Benzocaine HCl;4-amino-benzoic acid ethyl ester,hydrochloride;Ethyl p-aminobenzoate hydrochloride;Ethyl 4-aminobenzoate hydrochloride (1:1);benzoic acid, 4-amino-, ethyl ester, hydrochloride (1:1);MFCD00012999;Ethyl 4-aminobenzoate hydrochloride;Benzocaine hydrochloride;Benzoic acid,4-amino-,ethyl ester,hydrochloride;Benzocaine.HCl;94-09-7 (Parent)|
|Boiling Point:||118-119 °C(Press: 0.8 Torr)|
|Melting point:||291-292 °C|
|Appearance:||White crystal powder|
|Storage:||Inert atmosphere,Room Temperature|
|Storage:||Keep in dark place,Inert atmosphere,Room temperature|
What is benzocaine hydrochloride powder used for? /benzocaine hydrochloride uses
Benzocaine hydrochloride is an antimicrobial agent that belongs to the group of quaternary ammonium compounds. It is a local anesthetic and topical antiseptic that is used in topical formulations for the treatment of infectious diseases.
It is active against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. It has been shown to have no adverse effects on blood groups and has been found to be safe in toxicity studies.
This compound has been shown to have a direct effect on Na channels and may also inhibit the growth of bacterial cells by affecting their cell membranes. It can be obtained in crystalline form or as an amorphous solid, which may affect its rate of dissolution and therefore its clinical relevance.
What is the difference between benzocaine and benzocaine hydrochloride? /benzocaine hydrochloride vs benzocaine
Compared to benzocaine, benzocaine hydrochloride is more water soluble, making it more appropriate for oral administration.
benzocaine hydrochloride solubility in water
Water: Insoluble DMSO (Slightly), Water (Slightly)
benzocaine hydrochloride salt synthesis
Ethanol–>4-Aminobenzoic acid–>Ethyl p-nitrobenzoate–>Benzocaine
Benzocaine hydrochloride structure