CompoundsOrganic CompoundsSodium cyanoborohydride CAS 25895-60-7

SKU: WGP-25895-60-7

Sodium cyanoborohydride

CAS 25895-60-7

MF: CH3BNNa

hydride is a milder and more selective reducing agent than sodium borohydride.
Sodium cyanoborohydride is a weaker and more-selective reducing agent than sodium borohydride because of the electron-withdrawing effect of the cyano group. It has the further advantage that it is stable in acid to pH = 3 and can be employed to effect reductions in the presence of functional groups that are sensitive to the more-basic conditions of reduction with sodium borohydride.

Description

Sodium cyanoborohydride CAS 25895-60-7 Product Information

Product Name:Sodium cyanoborohydride
Synonyms:Sodium cyanoborohydride;sodium cyanohydroboride;Sodium cyanohydridoborate;MFCD00003516;sodium cyanoborohydride solution;EINECS 247-317-2;Sodium cyonobrohydriole;Sodium (cyano-κC)(trihydrido)borate(1-);SODIUM CYANOTRIHYDROBORATE;Borate(1-), (cyano-κC)trihydro-, sodium (1:1);sodium cyano borohydride;sodium borocyanohydride;SODIUM CYANOTRIHYDRIDOBORATE
CAS NO:25895-60-7
Molecular Weight:62.84
Molecular Formula:CH3BNNa
Boiling Point:307°C
Melting point:>242 °C (dec.) (lit.)
Density:1.083 g/mL at 25 °C
Appearance:White powder
Purity:>98%
Stability:Avoid contact with oxides, acids, moisture/humidity
Storage:Store under dry nitrogen or argon atmosphere.

sodium cyanoborohydride cas/sodium cyanoborohydride cas no

25895-60-7

Customized packaging on demand

sodium cyanoborohydride preparation

Synthesis of Sodium cyanoborohydride(NaBH3CN): NaBH3CN was made by stirring equimolar BH3·THF (~1 M) with NaCN in THF in excellent yield.To a rapidly stirred slurry of sodium borohydride (80.2g, 2.09 mol) in THF (1000mL) in a 2-L flask is added a solution of hydrogen cyanide in THF (294g containing 58.8g of hydrogen cyanide) at 25°C. Evolution of hydrogen occurs slowly during the addition. Following the addition, the reaction mixture is stirred for 1 h at 25°C and then heated at reflux until hydrogen evolution has ceased. Filtration followed by vacuum removal of THF gives white solid sodium cyanoborohydride; yield 120g (91%).

sodium cyanoborohydride mechanism/sodium cyanoborohydride reduction

Tin-free Giese reaction of alkyl iodides with electron-deficient alkenes and the related radical carbonylation process proceeded efficiently in the presence of sodium cyanoborohydride and tetrabutylammonium cyanoborohydride. Transfer of iodine followed by hydride reduction of the resulting carbon-iodine bond is proposed as a possible mechanism.

sodium cyanoborohydride quenching

The following views come from reddit:You can quench cyanide with bleach.Our factory and lab

sodium cyanoborohydride reductive amination

Sodium cyanoborohydride (NaBH3CN) is a mild reducing agent that is commonly used in reductive aminations. The presence of the electron-withdrawing cyano (CN) group makes it less reactive than sodium borohydride (NaBH4).

sodium cyanoborohydride vs sodium borohydride

Sodium cyanoborohydride (NaBH3CN) is a mild reducing agent that is commonly used in reductive aminations. The presence of the electron-withdrawing cyano (CN) group makes it less reactive than sodium borohydride (NaBH4).

sodium cyanoborohydride safety

Precautionary statement(s) P260 Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.transportation

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