Bupivacaine hydrochloride
CAS:14252-80-3
MF:C18H28N2O.ClH
Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus.
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Description
Bupivacaine hydrochloride CAS 14252-80-3 Product Information
Product Name: | Bupivacaine hydrochloride |
Synonyms: | BUPIVACAINEHYDROCHLORIDE;(+,-)-1-butyl-2’,6’-pipecoloxylididemonohydrochloride,monohydrate;Bupivacainehydrochloride1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamidehydrochloride;BupivacaineHydrochloride,ChemicalbookUSP;INSTOCKBUPIVACAINEHYDROCHLORIDECASNO.14252-80-3;BUPIVACAINEHYDROCHLORIDECASNO.14252-80-3;LocalAnestheticPharmaceuticalRawMaterialBupivacaineHClCAS14252-80-3;1-butyl-2’,6’-pipecoloxylididehydrochloride(+-) |
CAS NO: | 14252-80-3 |
Molecular Weight: | 324.89 |
Molecular Formula: | C18H28N2O.ClH |
Appearance: | White to Off-White Solid |
Melting point: | 249-251°C |
Solubility: | Soluble in water, freely soluble in alcohol. |
Storage: | Refrigerator |
Applications: | Bupivacaine hydrochloride is an amide-type local anesthetic, generally used for nerve block anesthesia, local infiltration anesthesia and epidural anesthesia. Its mechanism of action is similar to that of amide-type local anesthetics, i.e., the drug is first combined with plasma proteins, metabolized by the liver, and then excreted from the urine via the kidney. |
bupivacaine hydrochloride injection
Bupivacaine hydrochloride injection is a medication that is used to numb an area of your body during or after surgery or other procedures, childbirth, or dental work. It is also used to numb your shoulder after surgery for up to 72 hours. Bupivacaine hydrochloride injection contains bupivacaine hydrochloride, an amide local anesthetic. It is important to follow your doctor’s instructions when using this medication and to tell your doctor if you have ever had an allergic reaction to any type of numbing medicine.
bupivacaine hydrochloride uses
Bupivacaine hydrochloride injection is used to numb an area of your body during or after surgery or other procedures, childbirth, or dental work. It is also used to numb your shoulder after surgery for up to 72 hours. Bupivacaine hydrochloride injection contains bupivacaine hydrochloride, an amide local anesthetic.
bupivacaine hydrochloride action
Bupivacaine hydrochloride injection is a medication that is used to numb an area of your body during or after surgery or other procedures, childbirth, or dental work. Bupivacaine blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. It is available mixed with a small amount of epinephrine to increase the duration of its action.
bupivacaine hydrochloride dose
The dose of bupivacaine hydrochloride injection depends on the type of procedure being performed, the size of the area being numbed, and other factors. The usual adult dose for local infiltration is up to 175 mg without epinephrine. The usual pediatric dose for local infiltration is based on the child’s weight. It is important to follow your doctor’s instructions when using this medication and to tell your doctor if you have ever had an allergic reaction to any type of numbing medicine.
bupivacaine hydrochloride preparation
Bupivacaine hydrochloride injection is usually prepared by a healthcare professional in a hospital or clinic setting. The dose and preparation of bupivacaine hydrochloride injection depend on the type of procedure being performed, the size of the area being numbed, and other factors. It is important to follow your doctor’s instructions when using this medication and to tell your doctor if you have ever had an allergic reaction to any type of numbing medicine.
Additional information
Color | White |
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Form | Powder |
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