CompoundsOrganic CompoundsPyrrolidine CAS 123-75-1

SKU: WGP-123-75-1




Pyrrolidine is a flammable alkaline liquid that undergoes reactions typical of secondary amines. It is used to prepare pesticides and rubber accelerators and as a chemical intermediate (usually the hydrochloride form) in the pharmaceutical industry.

  • Description
  • Additional information


Pyrrolidine CAS 123-75-1 Product Information

Product Name:Pyrrolidine


CAS NO:123-75-1
Molecular Weight:71.121
Molecular Formula:C4H9N
Boiling Point:89.5±8.0 °C at 760 mmHg
Melting point:-63 °C
Density:0.8±0.1 g/cm3
Appearance:Colorless transparent liquid
Applications:Pyrrolidine is a heterocyclic compound used as a building block in the synthesis of wide range of

pharmaceutical compounds, namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase

N inhibitors (APNIs). It has been used for the synthesis of N-benzoyl pyrrolidine from benzaldehyde

via oxidative amination. It may be used as a catalyst for the synthesis of N-sulfinyl aldimines from

carbonyl compounds and sulfonamides.

Stability:Stable; flammable. Incompatible with strong acids, strong oxidizing agents.
Storage:Store in an airtight seal away from light. Packed in galvanized iron drums. The warehouse is cool and ventilated, keep away from fire, fire source, sunscreen, acid and oxidant.

pyrrolidine structure

Pyrrolidine is a cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family. It is a saturated organic heteromonocyclic parent, a member of pyrrolidines and an azacycloalkane. It is a conjugate base of a pyrrolidinium ion.

pyrrolidine synthesis

Laboratory synthesis

In the laboratory, pyrrolidine was usually synthesised by treating 4-chlorobutan-1-amine with a strong base:

Synthesis of pyrrolidine

Furthermore, 5-membered N-heterocyclic ring of the pyrrolidine derivatives can be synthesized via 

pyrrolidine sds/pyrrolidine msds

Hazard CodesF,T,C
Risk Statements11-22-23-34-35-20/21/22-20/22-R35-R20/21/22-R11
Safety Statements16-26-36/37/39-45-33-S45-S36/37/39-S26-S16
RIDADRUN 1922 3/PG 2
WGK Germany2
F20 °C
Autoignition Temperature34
TSCA653 °F
HS CodeYes
HazardClass2933 99 80

pyrrolidine alkaloids

Pyrrolizidine alkaloids (PAs) are heterocyclic organic compounds synthesized by plants that are thought to act as defense compounds against herbivores [1]. Estimates indicate that approximately 6.000 plant species worldwide, representing 3% of all flowering plants, produce these secondary metabolites.Our factory and lab

pyrrolidine pka

11.27(at 25℃)

pyrrolidine density/pyrrolidine density g/ml

0.8±0.1 g/cm3/0.852 g/mL at 25 °C (lit.)

pyrrolidine smell

Taste characteristics at 50 ppm: ammonia and fishy, amine-like with seaweed and shellfish nuances.transportation

Additional information

Melting Point

-63 °C

Boiling point 

87-88 °C(lit.)

Flash Point

37 °F







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