Ibutamoren(MK677) Cas No.159752-10-0

SKU: WGP-159752-10-0

CAS 159752-10-0
MF: C27H36N4O5S.CH4O3S
GRADE: Pharmaceutical grade
MOQ: 10G
  • Description
  • Additional information


What is MK 677 (Ibutamoren)

Ibutamoren (also known as ibutamoren mesylate or MK-677), is thought to promote the secretion of the growth hormone (GH) and increase insulin-like growth factor 1 (IGF-1).
Ibutamoren potentially increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Therefore, some people expect that ibutamoren may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren has on appetite – and as expected, like ghrelin, ibutamoren increases it.
According to some studies, ibutamoren could potentially increase growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

MK 677 (Ibutamoren) Benefits

  • Increases IGF-1 levels in as little as two weeks.
  • Longer REM sleep and much shorter sleep latency.
  • Increased fat-free muscle mass.
  • Decrease your body fat percentage.
  • Stronger bones.
  • Improved endurance.
  • Reversal of nitrogen wasting.
  • High nitrogen levels in the body.

MK 677 (Ibutamoren) side Effects

As an anabolic, ibutamoren should be avoided if you have cancer. Both growth hormone and IGF-1 may promote cancer growth.

The most frequent side effects of ibutamoren in the existing literature are increased appetite, mild lower extremity oedema, and muscle pain.

Several studies report an increase in fasting blood glucose and a decrease in insulin sensitivity.

These side effects are similar to those observed in people with elevated growth hormone levels, mainly joint pain and insulin resistance.

Although most studies report little or no side effects, one study was terminated because of serious adverse events. That’s a big deal and usually a sign that researchers considered the compound extremely unsafe. Stopping a clinical trial because of adverse events is a giant red flag and a very good reason not to take the compound in question.

Additional information






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