Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 and virginiamycin S1 produced by S. virginiae. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria.
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Virginiamycin CAS 11006-76-1 Product Information
|Synonyms:||Lactrol;VirginiamycinnnDISCONTINUED;N-(22-Benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl)-3-hydroxy-2-pyridinecarboxamide – (12Z,17Z,19Z)-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[18.104.22.168]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone (1:1);patricin;N-(22-Benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl)-3-hydroxy-2-pyridinecarboxamide – 21 ;-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[22.214.171.124]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone (1:1);eskalinv;skf7988;Livelong;mikamycin;2-Pyridinecarboxamide, N-[6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-22-(phenylmethyl)-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl]-3-hydroxy-, compd. with 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone (1:1);stafac500;Stafac;V-max;rp7293|
|Applications:||The Virginiamycin complex contains two streptomycin antibiotics, Virginiamycin M1 and Virginiamycin S1. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria|
|Storage:||Keep in dark place,Inert atmosphere,Room temperature|
Virginiamycin is a type A/B streptogramin antibiotic that is commonly used in veterinary medicine. It has a dual mode of action, targeting bacterial protein synthesis. Some of the main uses of virginiamycin include:
- Animal Feed Additive: Virginiamycin is commonly added to animal feed, particularly for poultry and swine, to promote growth and improve feed efficiency. It helps in preventing and controlling certain gastrointestinal infections in animals.
- Prevention of Necrotic Enteritis: Necrotic enteritis is a common bacterial disease in poultry caused by Clostridium perfringens. Virginiamycin is used to prevent and control this disease in poultry production.
- Control of Gram-Positive Infections: Virginiamycin is effective against various gram-positive bacteria, including Staphylococcus and Streptococcus species. It is used in veterinary medicine for the treatment and prevention of bacterial infections caused by these pathogens.
Virginiamycin is widely used in poultry farming as a feed additive. It helps promote growth, enhance feed efficiency, and prevent/control bacterial infections. Specifically, it is effective against necrotic enteritis caused by Clostridium perfringens. Its incorporation into poultry feed supports flock health and productivity. Regulatory guidelines must be followed to ensure proper dosage, administration, and minimize antibiotic resistance.
virginiamycin mode of action
Virginiamycin M1 is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation.
The macrolides are similar to the lincosamide and streptogramin B class of antibacterials, such as clindamycin and virginiamycin, respectively, in their interactions with ribosomes.