Surfactin is a cyclic lipopeptide biosurfactant that mediates the flux of monovalent and divalent cations, such as calcium ions, across lipid bilayer membranes. Surfactin acts as an antimicrobial adjuvant with antibacterial, antifungal, antimycoplasma, and hemolytic effects. Surfactin also has antiviral activity against a variety of enveloped viruses.
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Surfactin CAS 24730-31-2 Product Information
|Synonyms:||SURFACTIN;surfactin from bacillus subtilis;Surfactin peptide;surfactin C;Biosurfactants Surfactin;Cyclo(L-α-aspartyl-D-leucyl-L-leucyl-3-hydroxy-13-methyltetradecanoyl-L-α-glutamyl-L-leucyl-D-leucyl-L-valyl);Surfactin C1;abs9122|
|Boiling Point:||1268.3±65.0 °C(Predicted)|
|Applications:||Surfactin is a cyclic lipopeptide biosurfactant that mediates the flux of monovalent and divalent cations, such as calcium ions, across lipid bilayer membranes. Surfactin acts as an antimicrobial adjuvant with antibacterial, antifungal, antimycoplasma and hemolytic effects. Surfactin also has antiviral activity against a variety of enveloped viruses.|
|Solubility:||ethanol: 10 mg/mL, clear, slightly yellow|
Surfactin is a cyclic lipopeptide, commonly used as an antibiotic for its capacity as a surfactant. It is an amphiphile capable of withstanding hydrophilic and hydrophobic environments. The Gram-positive bacterial species Bacillus subtilis produces surfactin for its antibiotic effects against competitors.
surfactin in lungs
Surfactant is an agent that decreases the surface tension between two media. The surface tension between gaseous-aqueous interphase in the lungs is decreased by the presence of a thin layer of fluid known as pulmonary surfactant. The pulmonary surfactant is produced by the alveolar type-II (AT-II) cells of the lungs.
Biosurfactants are active compounds that are produced at the microbial cell surface or excreted, and reduce surface and interfacial tension. Microbial surfactants offer several advantages over synthetic ones, such as low toxicity and high biodegradability, and remain active at extreme pH and salinity.
Surfactin has a ring-shaped peptide chain containing seven amino acids, and a β-hydroxy fatty acid chain of 13–16 carbon atoms as shown in Fig. Because of some differences in the length of the fatty acid chain and the types of amino acids, surfactin has many congeners or isoforms.
surfactin antimicrobial activity
The isolated surfactin exhibits good antimicrobial activity (1600 AU/ml) against drug-resistant food-born B. cereus and human pathogen Staphylococcus aureus. Hence, identified strain B. velezensis SK and its potent antibacterial surfactin lipopeptide could be used in various food and biomedical applications.
bacillus subtilis surfactin/surfactin bacillus subtilis
Surfactin is a biosurfactant produced by Bacillus subtilis. The srfA operon, Sfp gene, and two quorum sensing systems are required for its production. The master regulator spo0A also plays an indispensable role in proper
It provides moisture, texture and glossy shine for hair, and can help for hair styling.
White to offwhite
Crystalline Powder or Crystalline Needles