CompoundsActive IngredientsSex Raw MaterialPrilocaine HCL CAS 1786-81-8

SKU: WGP-1786-81-8

Prilocaine Hydrochloride


Molecular Formula: C13H21ClN2O

Molecular Weight: 256.77


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Prilocaine HCL CAS 1786-81-8 Product Information

Product Name: Prilocaine Hydrochloride
Synonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide Hydrochloride; 2-(Propylamino)-o-propionotoluidide Hydrochloride; Citanest Hydrochloride; L 67; L 67 Hydrochloride; Prilocaine Chloride; Xylonest;
CAS NO: 1786-81-8
Molecular Weight: 256.77
Molecular Formula: C13H21ClN2O
Appearance: White to Off-White Solid
Melting point: 168-170°C
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Applications: Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry.Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.

What is Prilocaine HCL CAS 1786-81-8

Commonly used local anaesthetic in dental and medical operations is prilocaine hydrochloride, with CAS number 1786-81-8. The main salient features of Prilocaine hydrochloride are:

1. Prilocaine hydrochloride has C13H20N2O·HCl as its chemical formula and structure.
Its structure consists of an aromatic ring (toluidine) joined to a secondary amine and an amide group, therefore creating part of a substituted propyl chain.

2. Physical Characteristics:

  • Usually a white crystalline powder, prilocaine hydrochloride looks like
  • Solubility: It is quite soluble in water as well as in organic solvents including ethanol.
  • Melting point: 168– 170°C.

3. Prilocaine hydrochloride is a local anaesthetic of amide type. It acts by blocking sodium channels in neuronal membranes, therefore preventing conduction of nerve impulses and consequent loss of sensation in the intended location.

4. Medical Applications:

  • Local Anaesthesia: Prilocaine hydrochloride is used to give local anaesthesia for many surgical and dental operations, including minor surgeries, dental work, and diagnosis investigations.
  • Nerve blocks and epidural anesthesia—which provide pain relief in particular areas of the body—are forms of regional anaesthesia.
  • Prilocaine is sometimes used with lidocaine in topical anaesthetic creams (like EMLA cream) for skin numbing before surgeries including injections, minor operations, or laser treatments.

5. Dosage and Administration:

  • One injectable dose of prilocaine hydrochloride is The kind of operation, the area to be anaesthetized, and the patient’s condition all affect the dosage and concentration.
  • It is available in several formulations and dosages; occasionally it is mixed with other anestues or vasoconstrictors.

6. Safety and Side Effects:

  • Common side effects include localised reactions at the injection site including redness, swelling, or discomfort.Among the systematic side effects could include nausea, headache, vertigo, and drowsiness.Rarely may prilocaine hydrochloride cause serious allergic responses, cardiovascular problems (like arrhythmias), or central nervous system consequences (such convulsions).
  • One particular concern associated with prilocaine is methemoglobinemia, a disorder in which an aberrant methemoglobin synthesis results, therefore compromising blood’s oxygen-carrying ability.
  • Patients with heart illness, liver disease, or past hypersensitivity to local anaesthetics should exercise great caution. Patients with disorders that increase their likelihood of methemoglobinia should also avoid it. Management of possible side effects in administration depends on monitoring.
    Prilocaine hydrochloride ought to be kept away from light and moisture in a cold, dry environment. It should be handled following medical advice and kept out of reach for youngsters.

All things considered, Prilocaine hydrochloride is a good local anaesthetic applied in many dental and medical operations. Its quick start and modest duration of action make it useful for pain control. Its safe and efficient usage depends on correct administration, monitoring, and respect of safety standards.

Transit time You will normally receive your parcel within 7-15 working days after shipment (this may be delayed in special circumstances, such as Chinese New Year).
Receiving method Generally we will send the goods by courier or special line, of course, if the goods themselves in the local warehouse have goods, also support self-pickup, depending on the circumstances.
Overseas warehouse We have overseas warehouses in some European countries and Australia, such as Germany, Russia and Australia.
Delivery Method WGP will ship via courier companies such as DHL, FedEx, UPS, TNT or EMS.
About After Sales Within 7 days of your receipt of the goods if you find any problems with the goods (broken packaging, less hair, etc.) please feel free to contact our sales, we will help you deal with it in time.

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