N-acetylneuraminic acid is an N-acyl derivative of neuraminic or acid amino sugar derivative, derived from N-acetylmannosamine and pyruvic acid. It is an important constituent of glycoproteins and glycolipids. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
N-Acetylneuraminic acid CAS 131-48-6 Product Information:
|Product Name:||N-Acetylneuraminic acid|
|Synonyms:||5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid;NANA;5-(acetylamino)-3,5-dideoxy-δ-glycero-δ-galacto-2-Nonulosonic acid;NANA H2O;Sialomucin;sialic acid powder;Lactaminic acid;5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid;N-acetyl-D-neuraminic acid;5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid;5-Acetamido-3,5-dideoxy-D-glycero-D;galactononulosonic acid,Lactaminic acid,NAN;O-SIALIC ACID;NANA TYPE IV-S;NEU5AC;D-glycero-D-galacto-2-Nonulosonic acid, 5-(acetylamino)-3,5-dideoxy-;sialic acid;NANA TYPE VI;EINECS 205-023-1;5-(Acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic Acid;NAN;(4S,5R,6R,7S,8R)-5-Acetamido-4,6,7,8,9-pentahydroxy-2-oxononanoic acid;Aceneuramic acid;N-Acetylneuraminic acid;MFCD00006620|
|Boiling Point:||449.56°C (rough estimate)|
|Melting point:||184-186 °C|
|Density:||1.3580 (rough estimate)|
|Applications:||N-Acetylneuraminic acid is a sialic acid monosaccharide ubiquitous on glycoproteins of cell membranes and glycolipids of mammalian ganglioglycerides, and plays a biological role in neurotransmission, leukocyte vascular extravasation, and viral or bacterial infection.|
n acetylneuraminic acid synthesis
In bacterial systems, sialic acids are biosynthesized by an aldolase enzyme. The enzyme uses a mannose derivative as a substrate, inserting three carbons from pyruvate into the resulting sialic acid structure. These enzymes can be used for chemoenzymatic synthesis of sialic acid derivatives.
n acetylneuraminic acid uses
N-Acetylneuraminic acid is an integral part of sialic acids (SAs), important functional sugars that play an important role in maintaining and improving brain health, detoxification, antibacterial, and immune enhancement. n-Acetylneuraminic acid is biologically useful for neurotransmission, leukocyte extravasation, viral or bacterial infection, and carbohydrate-protein recognition. n- Acetylneuraminic acid is used to study its biochemistry, metabolism and absorption in vivo and in vitro.
n acetylneuraminic acid function
N-acetylneuraminic acid (NeuAc) is an indispensable part of sialic acids (SAs), which are important functional sugars and play an important role in maintaining and improving brain health, detoxification, antibacterial, boosting immune system and so on.
n acetylneuraminic acid is present in
N-Acetylneuraminic acid (Neu5Ac, termed sialic acid/SA here) is one of over thirty known sialic acid analogs. It is the predominant form of sialic acid in humans and is presented as the terminal residue on surface-exposed glycans, glycoproteins, and glycolipids.
n acetylneuraminic acid structure
n acetylneuraminic acid solubility
It is soluble in organic solvents such as DMSO and dimethyl formamide. The solubility of NANA in these solvents is approximately 1 and 0.1 mg/ml, respectively.
n acetylneuraminic acid is also called
IUPAC name. 5-(acetylamino)-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid. Other names. NANA.
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