N-acetylneuraminic acid is an N-acyl derivative of neuraminic or acid amino sugar derivative, derived from N-acetylmannosamine and pyruvic acid. It is an important constituent of glycoproteins and glycolipids. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
N-Acetylneuraminic acid CAS 131-48-6 Product Information:
|Product Name:||N-Acetylneuraminic acid|
|Synonyms:||5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid;NANA;5-(acetylamino)-3,5-dideoxy-δ-glycero-δ-galacto-2-Nonulosonic acid;NANA H2O;Sialomucin;sialic acid powder;Lactaminic acid;5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid;N-acetyl-D-neuraminic acid;5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid;5-Acetamido-3,5-dideoxy-D-glycero-D;galactononulosonic acid,Lactaminic acid,NAN;O-SIALIC ACID;NANA TYPE IV-S;NEU5AC;D-glycero-D-galacto-2-Nonulosonic acid, 5-(acetylamino)-3,5-dideoxy-;sialic acid;NANA TYPE VI;EINECS 205-023-1;5-(Acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic Acid;NAN;(4S,5R,6R,7S,8R)-5-Acetamido-4,6,7,8,9-pentahydroxy-2-oxononanoic acid;Aceneuramic acid;N-Acetylneuraminic acid;MFCD00006620|
|Boiling Point:||449.56°C (rough estimate)|
|Melting point:||184-186 °C|
|Density:||1.3580 (rough estimate)|
|Applications:||N-Acetylneuraminic acid is a sialic acid monosaccharide ubiquitous on glycoproteins of cell membranes and glycolipids of mammalian ganglioglycerides, and plays a biological role in neurotransmission, leukocyte vascular extravasation, and viral or bacterial infection.|
n acetylneuraminic acid uses
N-Acetylneuraminic acid, also known as sialic acid, has various uses and functions in biological systems. Some of its key uses include:
1. Glycoprotein Modification: N-Acetylneuraminic acid is a critical component of glycoproteins and glycolipids. It serves as a terminal sugar residue that plays a role in cell recognition, adhesion, and signaling.
2. Influenza Virus Receptor: The N-Acetylneuraminic acid present on the surface of host cells acts as a receptor for influenza virus attachment, facilitating viral entry into the host cells.
3. Brain Development: N-Acetylneuraminic acid is involved in brain development and neuronal function. It plays a role in neural cell adhesion and migration during brain development.
4. Immune System Function: N-Acetylneuraminic acid helps modulate immune responses by influencing cell-cell interactions and signaling pathways involved in immune regulation.
5. Diagnostic and Therapeutic Applications: N-Acetylneuraminic acid is used in diagnostic tests to identify and quantify certain diseases. It also has potential therapeutic applications, such as in the development of antiviral drugs and treatments for certain neurological disorders.
These are just a few examples of the uses and functions of N-Acetylneuraminic acid, highlighting its importance in various biological processes.
n acetylneuraminic acid function
N-acetylneuraminic acid (NeuAc) is an indispensable part of sialic acids (SAs), which are important functional sugars and play an important role in maintaining and improving brain health, detoxification, antibacterial, boosting immune system and so on.
n acetylneuraminic acid is present in
N-Acetylneuraminic acid (Neu5Ac, termed sialic acid/SA here) is one of over thirty known sialic acid analogs. It is the predominant form of sialic acid in humans and is presented as the terminal residue on surface-exposed glycans, glycoproteins, and glycolipids.