Lysergol is an ergot alkaloid that when used in combination with antibiotic nalidixic acid, can effectively inhibit Escherichia coli. It also maintains the potential to act on the 5-HT1/2 receptors and at α1-adrenergic receptors thus acting as a neuropsychiatric drug.
- Additional information
Lysergol CAS 602-85-7 Product Information
|Boiling Point:||397.54°C (rough estimate)|
|Density:||1.0398 (rough estimate)|
|Appearance:||off-white to beige crystalline powder|
lysergol uses/use of glycerol
Lysergol, also known as ergoline-8-carboxamide, is a chemical compound that belongs to the ergoline family of alkaloids. It has various uses and applications, including:
Research: Lysergol is commonly used in scientific research and laboratory studies as a reference compound for the evaluation of its pharmacological properties, such as its effects on receptors or enzymatic activities.
Precursor in the synthesis of other compounds: Lysergol can serve as a starting material or precursor in the synthesis of other ergoline derivatives or related compounds with potential pharmacological activities.
Analytical reference standard: Lysergol is used as a reference standard by analytical laboratories to identify and quantify ergoline alkaloids or related substances in various samples, such as plants, foods, or biological fluids.
Is Lysergol psychoactive, if so what are the effects?
It doesn’t mention anything on it’s effects at all, it says it’s not a pre-cursor to LSD, which doesn’t mean it’s not psychoactive.Since it’s legal I’m sure someone here could try some lol, although a quick search did not find any info on any effects of Lysergol, which makes me think it’s probably not psychoactive, although there you never know until you try it. I found no info on anyone experimenting with it either.
Is it possible to convert lysergol into LSA or lysergate?
I asked someone (who seems very knowledgeable) about this question and I got this answer: “It’s not easy. The alkene will usually be oxidized before the alcohol. Anhydrous hypochlorite/PTC systems might do it; this rxn can be very selective and gives the aldehyde. It works because ClO- is actually relatively inert in aprotic environments and also becomes a very strong nucleophile.From the aldehyde I think you might be able to use MnO2 and N-heterocyclic carbenes to produce the amide directly. Again this rxn is quite selective.However, there are no documented successes I’ve ever heard of.”
Google searching “amidation of aldehydes” or “oxidative amidation of aldehydes” yields some interesting results: https://pubs.acs.org/doi/10.1021/jo301252c
lysergol effects/side effects of lysergol
Irritating to eyes, respiratory system and skin. Severely toxic effects may result from the accidental ingestion of the material; animal experiments indicate that ingestion of less than 5 gram may be fatal or may produce serious damage to the health of the individual.
Lysergol is an alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at C-8.
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off-white to beige