Josamycin
CAS:16846-24-5
MF: C42H69NO15
Josamycin (EN-141) is a macrolide antibiotic with antibacterial activity against a variety of pathogens, such as bacteria. The dissociation constant Kd of Josamycin (EN-141) for ribosomes is 5.5 nM.A macrolide antibiotic produced by certain strains of Streptomyces narbonensis var. josamyceticus.Josamycin, is used as a macrolide antibiotic effective against a variety of pathogens.
- Description
- Additional information
Description
Josamycin CAS 16846-24-5 Product Information
| Product Name: | Josamycin |
| Synonyms: | Vilprafen;Wilprafen;Josamycin Solution, 100ppm;Josamycin for peak identification;3-Acetate 4B-(3-Methylbutanoate)leucoMycin V;LeucoMycin V, 3-acetate4B-(3-Methylbutanoate);Leucomycin V 3-acetate 4”-(3-methylbutanoate);YL-704A3 |
| CAS NO: | 16846-24-5 |
| Molecular Weight: | 827.99 |
| Molecular Formula: | C42H69NO15 |
| Boiling Point: | 763.27°C (rough estimate) |
| Melting point: | 131.5℃ |
| Density: | 1.1547 (rough estimate) |
| Appearance: | white to slightly yellow powder |
| Applications: | Josamycin (EN-141) is a macrolide antibiotic with antibacterial activity against a variety of pathogens, such as bacteria. The dissociation constant Kd of Josamycin (EN-141) for ribosomes is 5.5 nM. |
| Solubility: | Soluble in ethanol |
| Storage: | Inert atmosphere,Store in freezer, under -20°C |
josamycin uses/what is josamycin used for
Josamycin is used to study the modification of phagocytosis and cytokine production by macrolide antibiotics, immunomodulatory effects, the suppression of matrix metalloproteinase production as well as study bacteria protein synthesis at the level of the the 23S rRNA, 50S ribosomal subunit.
josamycin fda
It was approved by the FDA in 2003 for treatment of complicated skin and skin structure infections caused by susceptible aerobic Gram-positive organisms and for Staphylococcus aureus bacteraemia caused by MRSA.
josamycin dosage
Adult: 1-2 g daily in 2 or more divided doses.
josamycin indication
Josamycin is a macrolide antibiotic used for the treatment of various susceptible bacterial infections. A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
josamycin mycoplasma genitalium
The recommended treatment for all cases of Mgen is sequential two-step therapy with doxycycline, followed by an additional agent (either moxifloxacin or azithromycin).
Additional information
| Color | White to offwhite |
|---|---|
| Form | Crystalline Powder or Crystalline Needles |
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