CompoundsActive IngredientsJosamycin CAS 16846-24-5

SKU: WGP 16846-24-5

Josamycin

CAS:16846-24-5

Molecular Formula: C42H69NO15

Molecular Weight: 827.99

MOQ:1KG

Availability: On Order

Packaging: Regular packaging or customised

 

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Description

Josamycin CAS 16846-24-5 Product Information

Product Name: Josamycin
Synonyms: Vilprafen;Wilprafen;Josamycin Solution, 100ppm;Josamycin for peak identification;3-Acetate 4B-(3-Methylbutanoate)leucoMycin V;LeucoMycin V, 3-acetate4B-(3-Methylbutanoate);Leucomycin V 3-acetate 4”-(3-methylbutanoate);YL-704A3
CAS NO: 16846-24-5
Molecular Weight: 827.99
Molecular Formula: C42H69NO15
Boiling Point: 763.27°C (rough estimate)
Melting point: 131.5℃
Density: 1.1547 (rough estimate)
Appearance: white to slightly yellow powder
Applications: Josamycin (EN-141) is a macrolide antibiotic with antibacterial activity against a variety of pathogens, such as bacteria. The dissociation constant Kd of Josamycin (EN-141) for ribosomes is 5.5 nM.
Solubility: Soluble in ethanol
Storage: Inert atmosphere,Store in freezer, under -20°C

Pharmacological Properties

  • Mechanism of Action: Josamycin’s action is inhibition of bacterial protein synthesis. It hooks to the 50S subunit of the bacterial ribosome to inhibit peptides from translocation during translation, therefore halting bacterial development.
  • Spectrum of Activity: It works against some Gram-negative and a lot of Gram-positive bacteria. Treating infections brought on by Mycoplasma, Chlamydia, and ureaplasma especially benefits from it.

Medical Applications

  • Bronchitis, pneumonia, and sinusitis are among upper and lower respiratory tract illnesses treated with josamycin.
  • Skin and Soft Tissue Infections: It works well for treating cellulitis, erysipelas, and impetigo.
  • Treatment for sexually transmitted infections (STIs) brought on by Chlamydia and Ureaplasma is josamycin.
  • Oral and Dental Infections: Periodontitis and gingivitis are among the oral and dental ailments it treats.
  • Gastrointestinal illnesses brought on by compatible bacteria can be treated with it.

Safety and Side Effects

  • Common Side Effects: Gastrointestinal disorders including stomach aches, nausea, vomiting, and diarrhoea. Additionally possible are allergic responses like itching and a rash.
  • Serious Side Effects: Among rare but major side effects are severe allergic responses (anaphylaxis) and hepatotoxicity—liver damage.
  • Precautions: Patients with liver illness should especially utilise josamycin under great care. It is advised to track liver performance under treatment.

Handling and Storage

Storage: Store josamycin somewhere cool, dry, free from direct light and moisture. Children should never be able to access it.

Handling: Like all antibiotics, it should be taken as directed by a medical practitioner; the whole course of therapy should be followed to stop the emergence of antibiotic-resistant bacteria.

 

 

 

Transit time You will normally receive your parcel within 7-15 working days after shipment (this may be delayed in special circumstances, such as Chinese New Year).
Receiving method Generally we will send the goods by courier or special line, of course, if the goods themselves in the local warehouse have goods, also support self-pickup, depending on the circumstances.
Overseas warehouse We have overseas warehouses in some European countries and Australia, such as Germany, Russia and Australia.
Delivery Method WGP will ship via courier companies such as DHL, FedEx, UPS, TNT or EMS.
About After Sales Within 7 days of your receipt of the goods if you find any problems with the goods (broken packaging, less hair, etc.) please feel free to contact our sales, we will help you deal with it in time.

Additional information

Color

White to offwhite

Form

Crystalline Powder or Crystalline Needles

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