Hygromycin B
CAS:31282-04-9
MF: C20H37N3O13
Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus. It is active against E. coli (MIC = 150 μg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis.
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- Additional information
Description
Hygromycin B CAS 31282-04-9 Product Information
| Product Name: | Hygromycin B |
| Synonyms: | antihelmycin;hydromycinb;hygromix2.4;hygromix-8;hygrovetine;Hygromycin Solution;Hygromix;5-O-(2,3-O-(6-Amino-6-desoxyheptapyranosyliden)-beta-D-talopyranosyl)-desoxy-N’-methyl-D-streptamin |
| CAS NO: | 31282-04-9 |
| Molecular Weight: | 527.52 |
| Molecular Formula: | C20H37N3O13 |
| Boiling Point: | 608.13°C (rough estimate) |
| Melting point: | 160-180°C |
| Density: | 1.4252 (rough estimate) |
| Appearance: | faintly brown to brown powder |
| Applications: | Hygromycin B, a selective antibiotic effective against most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome |
| Solubility: | H2O: 50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 30 days. |
| Storage: | 2-8°C |
hygromycin b selection concentration
Hygromycin B antibiotic ensures effective positive selection of cells expressing the hygromycin resistance (hph) gene. In mammalian cells, the recommended working concentration range for hygromycin B is 100 – 500 µg/ml.
hygromycin b gold
Hygromycin B Gold is normally used at a concentration of 200 μg/ml, a 500-fold dilution from the stock solution.
hygromycin b for chickens/hygromycin b chickens
Hygromycin B is used in chickens as an aid in the control of infections of the following intestinal parasites: large roundworms (Ascaris galli), cecal worms (Heterakis gallinae) and capillary worms (Capillaria obsignata).
hygromycin b solubility/hygromycin b soluble
Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.
hygromycin a
Hygromycin A 163 is an antibiotic produced by cultures of several types of Streptomyces50 and is widely used against Gram-positive and Gram-negative bacteria.
hygromycin-b 4-o-kinase
Hygromycin B 4-O-kinase (EC 2.7.1.163, hygromycin-B kinase) is an enzyme with systematic name ATP:hygromycin-B 4-O-phosphotransferase.
Additional information
| Color | White |
|---|---|
| Form | Powder |
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