CompoundsActive IngredientsChlorhexidine Hcl CAS 3697-42-5

SKU: WGP- 3697-42-5

Chlorhexidine Hcl



ChEBI: Chlorhexidine hydrochloride is a member of guanidines.

  • Description
  • Additional information


Chlorhexidine Hcl CAS 3697-42-5 Product Information

Product Name: Chlorhexidine Hydrochloride
Synonyms: Chlorhexidine dihydrochloride >=98%;Chlorhexidini Hydrochloride;1,1’-hexamethylenebis(5-(p-chlorophenyl)-biguaniddihydrochloride;2,4,11,13-Tetraazatetradecanediimidamide;2,4,11,13-tetraazatetradecanediimidamide,n,n’’-bis(4-chlorophenyl)-3,12-diimin;2,4,11,13-Tetraazatetradecanediimidamide,N,N’’-bis(4-chlorophenyl)-3,12-diimino-,dihydrochloride;ArlacideH;Biguanide,1,1’-hexamethylenebis[5-(p-chlorophenyl)-,dihydrochloride
CAS NO: 3697-42-5
Molecular Weight: 703.83
Molecular Formula: C22H32Cl4N10
Solubility:  Sparingly soluble in water and in propylene glycol, very slightly soluble in ethanol (96 per cent).
Melting point: 111-116 °C
Density: 1.284[at 20℃]
Appearance: White Crystalline Solid
Storage: 2-8°C

Chlorhexidine Hcl uses

It belongs to the class of chemicals called bisbiguanides. Here’s some information about Chlorhexidine HCl:

Antimicrobial properties: Chlorhexidine HCl has broad-spectrum antimicrobial activity, meaning it is effective against a wide range of microorganisms, including bacteria, viruses, and fungi. It works by disrupting the cell membranes of these microorganisms, leading to their death or inhibition of growth.

Uses: Chlorhexidine HCl is commonly used as a topical antiseptic to clean and disinfect the skin before surgical procedures or injections. It is also used as a disinfectant for medical instruments and surfaces. In addition, it is found in mouthwashes and oral rinses for oral hygiene and in certain products for wound care.

Concentration and formulations: Chlorhexidine HCl is available in different concentrations and formulations, including solutions, gels, creams, and mouthwashes. The appropriate concentration and formulation depend on the intended use and the specific recommendation of a healthcare professional.

Duration of action: Chlorhexidine HCl has a prolonged duration of action, which means it continues to provide antimicrobial effects even after application. This sustained release of activity allows for longer-lasting protection against microbial colonization.

Precautions and side effects: While generally considered safe when used as directed, chlorhexidine HCl can cause certain side effects, such as skin irritation, allergic reactions, and staining of teeth or dental restorations. It should be used with caution in individuals with known sensitivities or allergies.

Prescription and over-the-counter availability: Depending on the concentration and formulation, chlorhexidine HCl is available both as a prescription medication and over-the-counter (OTC) product. OTC products with lower concentrations are typically used for oral hygiene purposes.

What is Chlorhexidine Hcl?

Chlorhexidine HCl, also known as chlorhexidine hydrochloride, is an antiseptic and disinfectant agent that is widely used in healthcare settings and personal care products.

Additional information

Melting Point

111-116 °C


Sparingly soluble in water and in propylene glycol, very slightly soluble in ethanol (96 per cent).






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