CompoundsActive IngredientsMepivacaine CAS 22801-44-1

SKU: WGP 22801-44-1



Molecular Formula: C15H22N2O

Molecular Weight: 246.35


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Mepivacaine CAS 22801-44-1 Product Information

Product Name: Mepivacaine
Synonyms: N-(2,6-Dimethylphenyl)-1-Piperidinecarboxamide;N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide; N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide;A pp because; USP/EP/BP
CAS NO: 22801-44-1
Molecular Weight: 246.35
Molecular Formula: C15H22N2O
storage temp:  -20°C Freezer
Melting point: 147-151°C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Appearance: White to Off-White Solid
Uses: It can be used in biological study of 2-adamantanamine produces prolonged spinal block in rats.

What is Mepivacaine CAS 22801-44-1

Mepivacaine, with the CAS NO 22801-44-1, is a local anesthetic extensively used in medical and dental treatments. The following are the essential aspects of Mepivacaine:

1. Chemical Structure and Formula:

  • Mepivacaine has a chemical formula of C15H22N2O.
  • The compound’s composition includes a phenyl group connected to a secondary amine and an amide group, which collectively form a piperidine ring.

2. Physical Properties:

  • Appearance: Mepivacaine is commonly observed as a white crystalline powder.
  • Solubility: The ability of a substance to dissolve in a solvent. This substance exhibits solubility in water as well as in many organic solvents, including ethanol and chloroform.
  • The melting point of the substance is around 255-258°C.

3. Pharmacological Properties:

Mepivacaine is classified as an amide-type local anaesthetic. The mechanism of action involves the inhibition of sodium channels in neuronal membranes, resulting in the prevention of nerve impulse conduction and subsequent loss of sensation in the specific location.

4. Medical Applications:

  • Local Anaesthesia: Mepivacaine is employed to administer local anaesthesia for a range of surgical and dental operations, encompassing minor surgeries, dental work, and diagnostic tests.
  • Regional Anaesthesia: This technique is employed to administer nerve blocks and epidural anaesthesia, which effectively alleviate pain in a targeted area of the body.

5. Dosage and Administration:

  • Mepivacaine is injected intravenously. The dosage and concentration are contingent upon the nature of the procedure, the specific region to be anaesthetized, and the patient’s overall condition.
  • The user did not provide any text. It is offered in various formulations, occasionally paired with a vasoconstrictor to extend its impact and minimise bleeding.

6. Safety and Side Effects:

  • Common Side Effects: These may encompass localised reactions such as discomfort, edoema, or redness at the injection site. Systemic adverse effects may manifest as vertigo, cephalalgia, emesis, and somnolence.
  • Severe Adverse Reactions: In rare cases, mepivacaine may lead to severe allergic responses, cardiovascular complications (such as irregular heartbeats), or central nervous system manifestations (such as seizures).
  • Precautions: This medication should be used cautiously in individuals who have heart illness, liver disease, or a previous history of hypersensitivity to local anaesthetics. Supervision is necessary while administering in order to handle possible negative consequences.

7. Handling and Storage:

Mepivacaine should be stored in a cool and dry environment, shielded from both light and moisture. It is imperative to store it in a location inaccessible to minors and to handle it in accordance with medical protocols.

To summarise, Mepivacaine is a commonly employed local anaesthetic that offers efficient pain alleviation for a range of medical and dental interventions. Its fast onset and moderate duration of action make it highly desired. Thorough management and supervision are crucial to guarantee both the safety and effectiveness.

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