CAS 319460-85-0
MF:C22H18N4OS
It is a VEGFR inhibitor (IC50s = 1.2, 0.25, and 0.29 nM for VEGFR1, -2, and -3, respectively). It also inhibits c-Kit and PDGFRβ (IC50s = 1.7 and 1.6 nM, respectively). It inhibits VEGF-induced migration of and tube formation by human umbilical vein endothelial cells (HUVECs).
Description
CAS 319460-85-0 Product Information
| Product Name: | CAS 319460-85-0 |
| Synonyms: | N-Methyl-2-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide;Benzamide, N-methyl-2-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;UNII-C9LVQ0YUXG;;Inlyta;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;10mg;N-Methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide;AG-013736 N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;Axtinib;AVERMECTINB;N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide; |
| CAS NO: | 319460-85-0 |
| Molecular Weight: | 386.47 |
| Molecular Formula: | C22H18N4OS |
| Boiling Point: | 668.9±55.0 °C(Predicted) |
| Melting point: | 213-215°C |
| Density: | 1.4 |
| Appearance: | white to tan Powder |
| Purity: | >98% |
| Storage: | room temp |
| Storage: | Keep in dark place,Inert atmosphere,Room temperature |
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