Efinaconazole Cas No.164650-44-6

SKU: WGP-164650-44-6

Cas 164650-44-6

Efinaconazole is a broad-spectrum triazole antifungal agent
  • Description
  • Additional information

Description

Product Name:

Efinaconazole

Synonyms:

KP 103

CAS:

164650-44-6

EINECS:

813-597-5

MF:

C18H22F2N4O

MW:

348.39

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What is Efinaconazole?

Efinaconazole is a broad-spectrum triazole antifungal agent with activity against Acremonium, Aspergillus, Candida, Cryptococcus, Epidermophyton, Fusarium, Microsporum, Paecilomyces, Pseudallescheria, Scopulariopsis, Trichophyton, and Trichosporon. It inhibits the growth of T. rubrum and T. mentagrophytes clinical isolates with MIC values ranging from ≤2.0 to 60 ng/ml and of C. Albicans isolates with MIC values ranging from ≤0.5 to >250 ng/ml. Efinaconazole inhibits sterol 14α-demethylase, which arrests ergosterol (Item No. 19850) biosynthesis at the fungal membrane. It inhibits ergosterol biosynthesis in T. mentagrophytes and C. Albicans with IC50 values of 7.0 and 0.40 ng/ml, respectfully. Topical formulations containing efinaconazole have been used for the treatment of onychomycosis.

Packing material for different products: Aluminium foil bag, HDPE bottle, Iron drum, or according to require

Shelf Life:  2 Years from production date

Additional information

Melting Point

156°C

Boiling point 

600.0±60.0 °C(Predicted)

Flash Point

9 °C

Density

1.332 g/cm3

Solubility 

H2O: 0.5 mg/mL

Color

White

Form

Powder

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