Cas 164650-44-6
Efinaconazole is a broad-spectrum triazole antifungal agent
- Description
- Additional information
Description
Product Name: | Efinaconazole |
Synonyms: | KP 103 |
CAS: | 164650-44-6 |
EINECS: | 813-597-5 |
MF: | C18H22F2N4O |
MW: | 348.39 |
What is Efinaconazole?
Efinaconazole is a broad-spectrum triazole antifungal agent with activity against Acremonium, Aspergillus, Candida, Cryptococcus, Epidermophyton, Fusarium, Microsporum, Paecilomyces, Pseudallescheria, Scopulariopsis, Trichophyton, and Trichosporon. It inhibits the growth of T. rubrum and T. mentagrophytes clinical isolates with MIC values ranging from ≤2.0 to 60 ng/ml and of C. Albicans isolates with MIC values ranging from ≤0.5 to >250 ng/ml. Efinaconazole inhibits sterol 14α-demethylase, which arrests ergosterol (Item No. 19850) biosynthesis at the fungal membrane. It inhibits ergosterol biosynthesis in T. mentagrophytes and C. Albicans with IC50 values of 7.0 and 0.40 ng/ml, respectfully. Topical formulations containing efinaconazole have been used for the treatment of onychomycosis.
Packing material for different products: Aluminium foil bag, HDPE bottle, Iron drum, or according to require
Shelf Life: 2 Years from production date
Additional information
| Melting Point | 156°C |
|---|---|
| Boiling point | 600.0±60.0 °C(Predicted) |
| Flash Point | 9 °C |
| Density | 1.332 g/cm3 |
| Solubility | H2O: 0.5 mg/mL |
| Color | White |
| Form | Powder |
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