It was recently shown that acetaminophen, like aspirin, inhibits cyclooxygenase action in the brain and is even stronger than aspirin. On the other hand, the mechanism of analgesic action of acetaminophen is not fully clear, since it acts poorly on peripheral cyclooxygenase.
- Additional information
Acetaminophen CAS 103-90-2 Product Information
|Synonyms:||OL POWDER PB/USP;PARACETAMOL BP98;PARACETAMOL USP23,BP98;PARACETAMOL POWDER BP2000;PARACETAMOL BP98/USP24;n-(p-hydroxyphenyl)-acetamid;napa(analgesic);Napafen|
|Boiling Point:||387.8±25.0 °C at 760 mmHg|
|Melting point:||168-172 °C(lit.)|
|Appearance:||White Crystals or Crystalline Powder|
|Applications:||It is an effective antipyretic and analgesic that is well tolerated at therapeutic doses. It has only weak antiinflammatory activity; thus, it is not useful in the treatment of rheumatoid arthritis and other inflammatory conditions.|
|Solubility:||ethanol: soluble0.5M, clear, colorless|
|Storage:||Inert atmosphere, Room Temperature|
acetaminophen vs ibuprofen
Acetaminophen and ibuprofen are both commonly used over-the-counter medications for pain relief and fever reduction, but they belong to different drug classes and work in different ways.
- Acetaminophen is an analgesic (pain reliever) and antipyretic (fever reducer).
- It effectively reduces pain and fever but has little anti-inflammatory effect.
- It is commonly used for headaches, minor body aches, and reducing fever.
- Acetaminophen is generally considered safe when used as directed, but it can cause liver damage if taken in high doses or combined with alcohol.
- Ibuprofen belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs).
- It has analgesic, antipyretic, and anti-inflammatory properties.
- Ibuprofen is effective in reducing pain, fever, and inflammation.
- It is commonly used for conditions such as muscle pain, menstrual cramps, headaches, and joint pain caused by arthritis.
- Ibuprofen can cause side effects such as stomach irritation, ulcers, and increased risk of bleeding, especially when used at high doses or for a prolonged period.
acetaminophen vs paracetamol
Acetaminophen and paracetamol are actually the same medication but known by different names in different regions. Acetaminophen is the common name used in the United States and Canada, while paracetamol is the name commonly used in many other countries, including the United Kingdom, Australia, and parts of Europe. The chemical name for this compound is N-acetyl-para-aminophenol (APAP).
Acetaminophen/paracetamol is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). It is commonly used to relieve mild to moderate pain and reduce fever. Acetaminophen/paracetamol works by inhibiting the production of certain chemicals in the body that are involved in pain and fever. It is considered safe when used as directed, but it is important to follow the recommended dosage and avoid exceeding the maximum daily dose to prevent potential liver damage.
Acetaminophen and codeine are often combined in a single medication for the treatment of moderate to severe pain. Acetaminophen is a pain reliever and fever reducer, while codeine is an opioid analgesic.
The combination of acetaminophen and codeine works by enhancing the pain-relieving effects of both medications. Acetaminophen helps to reduce pain and fever, while codeine acts on the central nervous system to provide additional pain relief.
This combination medication is commonly prescribed for conditions such as dental pain, post-operative pain, and certain types of injuries. It is important to note that codeine is an opioid and carries the risk of addiction, abuse, and respiratory depression. Therefore, it should be used with caution and under the supervision of a healthcare professional.
Is acetaminophen an nsaid?
This OTC medicine is not an NSAID; it can ease mild-to-moderate pain and bring down a fever, and it tends to cause fewer stomach problems than other OTC pain relievers. But, unlike NSAIDs, it does not treat inflammation.
132 °C / 4mmHg
14 g/L (20 ºC)