Glatiramer Acetate CAS NO 147245-92-9

SKU: WGP-147245-92-9

CAS 147245-92-9
MF: C25H45N5O13
FW: 623.66
  • Description
  • Additional information


CAS NO147245-92-9
Chemical NameGlatiramer acetate
SynonymsProtiraMer;GlatiraMer-d7;GaltiraMer acetate;GLATIRAMER ACETATE;Glatiramer acetate USP/EP/BP;Glatiramer acetate [USAN:BAN];Pharmaceutical Glatiramer acetate;511: PN: WO2010103292 PAGE: 64 claiMed sequence;L-Alanine polyMer with L-GlutaMic Acid L-Lysine L-Tyrosine Acetate;L-Tyrosine polyMer with L-Alanine L-GlutaMic Acid L-Lysine Acetate
Molecular FormulaC25H45N5O13
Formula Weight623.66
AppearanceA crystalline solid
SolubilityPBS (pH 7.2): 1 mg/ml
ShippingRoom Temperature in continental US; may vary elsewhere
Stability≥ 2 years


Glatiramer (acetate) is a mixture of synthetic polypeptides composed of four amino acids found in myelin basic protein (MBP): L-Alanine, L-glutamic acid, L-lysine, and L-tyrosine. It prevents MBP from binding to MHC class II molecules in the periphery and induces the production of immunomodulatory molecules considered to be anti-inflammatory. It also increases proliferation of oligodendrocyte and neuronal precursor cells in the central nervous system of mice. Formulations containing glatiramer (acetate) are used to treat patients with multiple sclerosis, particularly the relapsing-remitting type.


Copaxone,Teva Pharmaceuticals,Israel


Glatiramer acetate is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine in a molar ratio of 6:1.9:4.7:1. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.

Manufacturing Process:

Glatiramer Acetate is water soluble copolypeptide with molecular weight 15,000-25,000.

Copolymer is prepared by copolymerization of the N-carboxyanhydrides of tyrosine, alanine, lysine, and glutamic acid. The polymerisation was carried out at ambient temperature in anhydrous dioxane with diethylamine as initiator. Glatiramer Acetate have the ratio alanin:glutamic acid:lysine:tyrosine = 1:6:4.54:2.

Therapeutic Function:


Additional information




Crystal powder


    There are no reviews yet.

    Be the first to review “Glatiramer Acetate CAS NO 147245-92-9”

    error: Alert: Content is protected !!